Microwave-Assisted Solvent Free Synthesis of Spiro-Indole Derivative
A solid supported synthetic procedure has been developed for the synthesis of novel spiro indole derivatives using solid support as energy transfer medium under microwave irradiation (MWI). The results were compared with those obtained by the classical as well as solution phase method in MWI. This solvent-free technique coupled with the high yields and short reaction time makes this procedure eco-friendly for synthesis.
Keywords: Spiro indoles; Microwave irradiation; 1HNMR; IR
Journal of Nepal Chemical Society Vol. 24, 2009 Page: 49-52
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