Phytochemical and Biological Studies on Zanthoxylum Armatum of Nepal

  • Sushika Joshi Central Department of Chemistry, Tribhuvan University, Kirtipur
  • Anuradha Gyawali Central Department of Chemistry, Tribhuvan University, Kirtipur
Keywords: Zanthoxylum armatum, Cytotoxic activity, Anti-bacterial property, ?-sitosterol, Lupeol, ?- sitosterol glycoside

Abstract

Phytochemical and biological screening of stem extracts of Zanthoxylum armatum of Nepal were carried out. Presence of sterols, triterpenes, volatile oils, coumarins, alkaloids, flavonoids, flavonic glycosides, saponins and tannins were detected in phytochemical screening. β-sitosterol and lupeol were isolated from the hexane fraction and β-sitosterol glucoside was isolated from the ethyl acetate fraction. Lupeol was identified by comparison of melting point, Co-TLC and 1H-NMR spectrum with authentic sample. β-sitosterol and β-sitosterol glucoside were characterized by their melting points and Co-TLC with authentic samples. In brine-shrimp bioassay, hexane and methanol fractions exhibited bioactivity, whereas ethyl acetate and methanol fractions showed proper bioactivity in antimicrobial bioassay.

DOI: http://dx.doi.org/10.3126/jncs.v30i0.9339

Journal of Nepal Chemical Society

Vol. 30, 2012

Page:  71-77

Uploaded date: 12/16/2013

 

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Abstract
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Published
2013-12-16
How to Cite
Joshi, S., & Gyawali, A. (2013). Phytochemical and Biological Studies on Zanthoxylum Armatum of Nepal. Journal of Nepal Chemical Society, 30, 71-77. https://doi.org/10.3126/jncs.v30i0.9339
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