Nosocomial Sepsis and its Risk Factors: A Cross-Sectional Study in a Neonatal Intensive Care Unit

  • Sunil Kumar Yadav BP Koirala Institute of Health Sciences, Dharan, Nepal
  • SP Yadav BP Koirala Institute of Health Sciences, Dharan, Nepal
  • P Kanodia BP Koirala Institute of Health Sciences, Dharan, Nepal
  • N K Bhatta BP Koirala Institute of Health Sciences, Dharan, Nepal
  • R R Singh BP Koirala Institute of Health Sciences, Dharan, Nepal
  • B Khanal BP Koirala Institute of Health Sciences, Dharan, Nepal
Keywords: Nosocomial sepsis, Neonatal intensive care unit, Risk factors

Abstract

Introduction: Nosocomial sepsis is a common and serious infection of neonates who are admitted in intensive care unit. They lead to significant morbidity and mortality in both developed and resource limited countries. The neonatal intensive care unit (NICU) is a suitable environment for disseminating the infections and, hence, needs preventive intervention. The study was carried out to determine the risk factors for nosocomial sepsis in neonatal intensive care unit.

Material and Methods: This was a cross-sectional study conducted in a seven bedded teaching and referral hospital NICU. All neonates in NICU who did not have any sign of infection at admission and remained hospitalized for at least 48 hours were observed. Nosocomial sepsis was diagnosed according to the CDC criteria. Risk factors for nosocomial sepsis were analyzed with Chi-square test and Logistic regression model. P-value of <0.05 was considered significant.

Results: Low birth weight (both preterm and IUGR) and mechanical ventilation were found to be related with nosocomial sepsis.

Conclusions: Low birth weight and mechanical ventilation were the most important risk factors fornosocomial sepsis.

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Author Biographies

Sunil Kumar Yadav, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Pediatrics and Neonatology

SP Yadav, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Pediatrics and Adolescent Medicine

P Kanodia, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Pediatrics and Adolescent Medicine

N K Bhatta, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Pediatrics and Adolescent Medicine

R R Singh, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Pediatrics and Adolescent Medicine

B Khanal, BP Koirala Institute of Health Sciences, Dharan, Nepal

Department of Clinical Microbiology and Infectious Diseases

Published
2019-07-24
How to Cite
Yadav, S., Yadav, S., Kanodia, P., Bhatta, N., Singh, R., & Khanal, B. (2019). Nosocomial Sepsis and its Risk Factors: A Cross-Sectional Study in a Neonatal Intensive Care Unit. Journal of BP Koirala Institute of Health Sciences, 2(1), 52-59. https://doi.org/10.3126/jbpkihs.v2i1.24970
Section
Original Articles