Cervical pap smear- A prospective study in a tertiary hospital

  • S Pudasaini Nepal Medical College Teaching Hospital, Kathmandu, Nepal
  • KBR Prasad Nepal Medical College Teaching Hospital, Kathmandu, Nepal
  • SK Rauniyar Nepal Medical College Teaching Hospital, Kathmandu, Nepal
  • R Pathak Nepal Medical College Teaching Hospital, Kathmandu, Nepal
  • K Pande Nepal Medical College Teaching Hospital, Kathmandu, Nepal
  • S Koirala Nepal Medical College Teaching Hospital, Kathmandu, Nepal
  • S Kafle Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Keywords: Cervical cancer, pap smear, screening, Bethesda system, intraepithelial lesion, malignancy

Abstract

Background: Cervical cancer is a leading cause of mortality and morbidity among women worldwide and most common gynaecological cancer in developing countries. Papanicolaou smear is a simple and cost effective screening test for cervical cancer. The aim of this study is to evaluate and interpret the cervical pap smear cytology in a tertiary hospital. The interpretation and reporting of the pap smear is based on 2001Bethesda system.

Materials and methods: This is a prospective study conducted in a tertiary hospital, Nepal Medical College over a period of two and a half years (January 2013 to June 2015). All cervical pap smears received in the department of Pathology in the study period were included.

Results: A total of 4160 cervical pap smears were reported in the study period. Majority of the cases were Negative for Intraepithelial lesion or malignancy (87.9%). Bacterial vaginosis, atrophy and reactive cellular changes associated with inflammation were seen in 5.3%, 2.4% and 1.5% cases respectively.   Epithelial cell abnormalities (0.5%) include Atypical squamous cells of undetermined significance, Low grade squamous intraepithelial lesion and High grade intraepithelial lesion. 88% of Low grade squamous intraepithelial lesion was seen in reproductive age group (20-45 years).

Conclusion: Cervical cancer is the most common gynaecological cancer in the developing countries. Pap smear is the simple and cost effective screening tool to detect pre invasive cervical epithelial lesions.

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Author Biographies

S Pudasaini, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
KBR Prasad, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
SK Rauniyar, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
R Pathak, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
K Pande, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
S Koirala, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
S Kafle, Nepal Medical College Teaching Hospital, Kathmandu, Nepal
Pathology
Published
2015-09-14
How to Cite
Pudasaini, S., Prasad, K., Rauniyar, S., Pathak, R., Pande, K., Koirala, S., & Kafle, S. (2015). Cervical pap smear- A prospective study in a tertiary hospital. Journal of Pathology of Nepal, 5(10), 820-823. https://doi.org/10.3126/jpn.v5i10.15639
Section
Original Articles